SpaceX CRS-19 Research Overview: Mighty Mice in Space
On SpaceX CRS-19, the Jackson Laboratory is sending to station 40 female mice, including a few that lack the gene for producing myostatin, a growth factor that normally acts to limit muscle growth in both mice and humans. These mutant mice lacking myostatin, dubbed “mighty mice,” develop additional muscle mass compared with normal mice. This investigation will examine the potential benefits of targeting the myostatin signaling pathway to help prevent diseases on Earth that result in muscle and bone loss. Microgravity induces rapid muscle and bone loss, providing accelerated models of disease for research aimed at improving therapeutics for patients on Earth.
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